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Andrew Zed Mason

Biological Sciences / California State University, Long Beach

About me

Associate Dean for Research and External Support

Professor of Biological Sciences

Director Institute for Integrated Research in Materials Environments and Societies (IIRMES) http://www.iirmes.org/Home


The primary focus of our research at the Molecular Toxicology Laboratories at CSULB is to study the effects of anthropogenic chemicals and pollutants on aquatic organisms and the ecosystems in which they dwell.

Areas of current research include elucidating the molecular and cellular mechanisms of entry of pollutants into aquatic organisms and determining their ultimate fate and impact on the health of the individuals and the community structures they inhabit.

Current projects in this area include studies on the uptake, bioaccumulation and excretion of specific classes of metals and xenobiotics compounds by organisms and their biotransformation and metabolism.

The metabolism and the biochemical and molecular mode of toxicological action of these compounds are also being studied in relation to physiological and genetic phenomena such as toxicological acclimation, adaptation and resistance .

Areas of interest / keywords

Publications

1. Mason, A.Z., A. Cabrera, E. Alonzo, E. Sauble, Y. Chu, M. Linder, and D.S. Sato. 2008. Copper binding components of serum and cytoplasm, copper turnover and excretion, and their responses to influx of large doses of 65Cu, in the mouse. BioMetals ISSN 0966-0844 (Print) 1572-8773 (Online). DOI10.1007/s10534-008-9139-6. (article)

2. Mason, A.Z., R. Moeller, Thrippleton, and D. Lloyd. 2007. The use of stable-isotopically labeled proteins and directly coupled HPLC-ICP-MS for quantitatively monitoring the transfer of metals between proteins. Anal. Biochem 369: 87-104. (article)

3. Mason, A.Z., T. Potter, J. Webster, and R.F. Meraz. 2005. Metalloprotein Crosstalk: Quantifying Zn atom exchange between isotopically labeled proteins using directly coupled HPLC-ICPMS. In: Plasma Source Mass Spectrometry, Current Trends and Future Developments. The Royal Society of Chemistry Special Publication 301: 3-27. (article)

4. Mason, A.Z. and D.J. Reish. 2003. Radiocarbon dating and Metal Analysis of "fossil" and living calcareous tubes of Protula (Annelida: Polychaeta). Hydrobiologia 496: 371-383. (article)

5. Mason, A.Z., J.A. Baca, A.B. De la Ree, and F. Zhou. 2003. Anodic stripping voltametrry combined on line with ICP-MS via a direct injection high efficiency nebulizer. Anal. Chem 75: 2507-2511. (article)

6. Mason, A.Z., S. Furata, F. Oritz, X. Sun, H. Wu, and J. Momad. 2002. Copper uptake is required for pyrrolidine dithiocarbamate mediated oxidation and protein level increase of p53 in cells. Biochem. J. 365: 639-648. (article)

7. Mason, A.Z. and M.R. Borja. 2002. Cu turnover in proteins of the visceral complex of Littorina littorea by stable isotopic analysis using coupled HPLC/ICP-MS. Mar. Environ. Res. 54: 351-355. (article)

8. Mason, A.Z. and R. Meraz. 1998. Cytosolic metal speciation, studies by sequential, on-line, SE-IE/HPLC-ICPMS. Mar. Environ. Res. 46: 573-577. (article)

9. Mason, A.Z. and K. Jenkins. 1995. Metal Speciation and Bioavailability in Aquatic International Union of Pure and Applied Chemistry series (IUPAC). Chapter 10: Metal Detoxification in Aquatic Organisms. Pp 479-609. J. Wiley Publishers. (Eds. A. Tessier and D.R. Turner). (article)

10. Mason, A.Z., S.D. Storms, and K.D. Jenkins. 1990. Metallothionein separation and analysis by directly coupled size exclusion high performance liquid chromatography inductively coupled plasma mass spectroscopy. Anal. Biochem(186): 187-201 . (article)

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